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Genetic Testing for MTHFR and Other Genes

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Where To Order Tests for MTHFR
Recommended Order of Treating Genetic Mutations
Videos To Watch:
Personalized 23andMe Methylation Analysis Demo Part 1
Personalized 23andMe Methylation Analysis Demo Part 2
Genetics 101 (Part 1 of 5): What are genes?
Genetics 101 (Part 2 of 5) What Are SNP's?
Genetics 101 (Part 5 of 5) Where Do Your Genes Come From?
Genetics 101 (Part 4 of 5) What Are Phenotypes?
Genetics 101 (Part 5 of 5) What Are Genes?

Where to Order MTHFR Tests
You can only know  for certain if you have this MTHFR mutation with blood or saliva testing, which is done only once in a lifetime. Labs that test for MTHFR with blood or saliva look at your unique DNA sequence to determine if one or both copies of your genes have a mutation at a specific location in a specific gene. 

These labs tests are available directly as listed below:

1.  23 and Me Test:

  • Sample: Saliva and Cheek Swab (for infants and young children)
  • NO Blood draw needed
  • Turnaround time: 6 to 8 weeks but may take longer due to volume
  • Price: $99 for first test and 20% discount for additional tests
  • Tests for MTHFR A1298C and MTHFR C677T and various other MTHFR snps PLUS numerous other genetic polymorphisms
  • International availability for many countries

  • Note: saves close to a million pieces of genetic data from your DNA. The test is easy, and there is no doctor needed.
    Just go to, order a kit, spit in a tube, and they run your DNA through their lab. This company has a database of over 400,000 people and provides comprehensives ancestry reports. 
    FDA Current Ruling: Unfortunately, because of recent concerns from the FDA, is not currently able to provide health-related related data.
    However, they still provides you full access to your raw data. This means that when you order your kit, you will be able to use Genetic Genie or other for methylation and detox profiles.

2. Spectracell Labs MTHFR Test:

  • Sample: Blood
  • Blood draw needed
  • Turnaround time: 3 to 5 weeks
  • Price: $195.95
  • Tests for MTHFR A1298C and MTHFR C677T
  • International availability. USA customers have prepaid return shipping label. Overseas customers must pay for self for return shipping.

3. Molecular Testing Labs MTHFR Test

  • Sample: Cheek Swab
  • NO Blood draw needed
  • Turnaround time:  3 to 5 days
  • Price: $150
  • Tests for MTHFR A1298C and MTHFR C677T
  • International availability

Methods to Analyze Your MTHFR and Genetic Raw Data Test Results:

  1. Genetic Genie: Once you get the analysis from 23andMe, you can UPLOAD it to for a free (donations are accepted).
    This website automates a methylation gene analysis just by reading your 23andMe raw data. Simply click on the Methylation Analysis tab, upload your data, and you’ll receive your results.

  2. The Livewello Gene App: Once you get the analysis from 23andMe, you can UPLOAD it to to free for a detailed report.
    The Livewello Gene App is a Variance Report Software that will run your 23andMe Genome, and generates your Phenotype for an unlimited number of Single Nucleotide Polymorphisms (SNPs).

    To use the App they can go to:

    How To Use the App (No need to Download raw Data, App will do it automatically):

    How To Share your Livewello Gene Report with your Practitioner:

    Everything You Ever Needed to Know About What To Do with Your 23andMe Raw Data

  3. Sterling's App: Another option for support is Sterling’s App. Each report costs $20.00.
    This helps you better understand your 23andMe results.  They offer an extensive chart for your SNPs (Single-nucleotide polymorphism) that you and your health practitioner can further investigate to setup an individual-based treatment plan.  These reports are "the most comprehensive and accurate available", containing sections on eye health, detox, tongue tie/cleft palate, methylation, allergy/mold, IgE, IgA, IgG, clotting disorders, thyroid, celiacs/gluten intolerance, mitochondrial function and sulfonotransferase genes.

Recommended Order of Treating Genetic Mutations

  1. SHMT mutation if present

  2. then ACAT if present

  3. then CBS mutation if present (gold) at the top of the transulphuration pathway. 
    This results in too much homocysteine and everything downstream is short of ingredients to do it's functions.  Producing too much ammonia and too much taurine is a problem.

  4. Next comes NOS (blue) mutation if present

Watch Videos About Genetic Testing

Personalized 23andMe / Methylation Analysis Demo Part 1
(14:35 minute)


Personalized 23andMe Methylation Analysis Demo Part 2
(8:40 minutes)


Genetics 101 (Part 1 of 5): What are genes?
(4:25 minutes)

Genetics 101 (Part 2 of 5) What Are SNP's?
(2:00 minutes)

Genetics 101 (Part 3 of 5): Where Do Your Genes Come From?
(4:20 minutes)

Genetics 101 (Part 4 of 5): What Are Phenotypes?
(2:03 minutes)

Genetics 101 (Part 5 of 5): Why No Y?
(1:10 minutes)


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