Polysorbate 80 is surfactant
that is Tween 80, Polyoxyethylene (20) sorbitan monooleate, and POE (20)
sorbitan monooleate. It is a brain toxic excipient added to vaccines and medications that crosses
the blood brain barrier. It allows nano particles to enter the brain, causing
inflammation. Polysorbate 80 (brand names include Alkest, Canarcel and
Tween, which is a registered trademark of ICI Americas, Inc.) is a nonionic
surfactant, a compound which lowers the surface tension between two liquids or
between a liquid and a solid. Surfactants may act as detergents, wetting agents,
emulsifiers, foaming agents, and dispersants.
Current Uses of Polysorbate 80
Polysorbates are widely used
in cosmetics, food products, and oral, parenteral, and topical
pharmaceutical formulations. It is generally regarded as nontoxic and
nonirritant materials. However, been occasional reports of hypersensitivity
to polysorbates following their topical and intramuscular use. Polysorbates
have also been associated with serious adverse effects, including
some deaths, in low birth weight infants intravenously administered a
vitamin E preparation containing a mixture of polysorbates 20 and 80.
Polysorbate 80 is used as an
emulsifier by the pharmaceutical industry to enhance the delivery of
chemicals and drugs from the blood into the brain across the blood brain
barrier (BBB). Being that the BBB is impermeable to many things in the
bloodstream, researchers needed to find a way to deliver chemicals/drugs
into the brain from the bloodstream in order to treat hard-to-reach brain
infections/lesions/tumors, etc.
Polysorbate 80 is one such
chemical that helps in this delivery.
Read more here.
Why Is Polysorbate 80
Dangerous?
They primary danger of
polysorbate 80 (Tween 80) is that it helps deliver compounds and this
includes mercury and aluminum, across the blood-brain barrier (BBB). The
blood-brain barrier is weak and easily crossed during the first two or three
years of life and often during the senior years. In other age groups the
blood-brain barrier which normally restricts passage of substances from the
bloodstream. Polysorbate 80 in vaccines may allow other vaccine ingredients
to enter the brain.
Polysorbate 80 is more dangerous
when combined with other risky vaccine ingredients. It is present
in DTaP, Gardasil (HPV), Hep A, Influenza
vaccines, Meningitis, Polio, Pneumococcal, Rotavirus, Tdap and
Vitamin K shots, as well as other vaccines and medications.
Polysorbate 80 is used as a
vaccine emulsifier. Many studies confirm that polysorbate 80 can increase
cell permeability, damage and bursting.
Polysorbate 80 may increase increase
the risk of diabetes as well as cell death, mitochondrial failure
and DNA fragmentation. After injection in a vaccine, it
can quickly break down into sorbitol and ethylene oxide. Sorbitol is
connected with these aforementioned risks.
Polysorbate 80 from vaccines has
also been shown to abruptly change heart function. A drug used
to treat anemia related to chronic kidney disease and chemotherapy warns:
Clinical studies have shown polysorbate 80 to increase the risk of serious
side effects such as blood clots, stroke, heart attack, heart failure and
death in some cases.
Polysorbate 80 has also been
shown to shorten overall survival and/or increase the risk of
tumor growth or recurrence in those with certain types of cancer.
Polysorbate 80 can cause
hypersensitivity reactions and anaphylaxis. It is very risky in
infants. The risk is increases when polymyxin B, another vaccine
ingredient is also present.
Polysorbate 80 is more dangerous for infants through the Vitamin K shot and
other childhood vaccines. It is made from
sorbitol, a plant-based sugar alcohol and oleic acid, a fatty acid.
It’s used in ice cream to make it smoother and it serves a similar purpose
in the vitamin K shot. It is an emulsifier, helping fat-soluble vitamin K
stay in solution. The ingredients in a Vitamin K shot with NO preservatives
include 10 mg of polysorbate 80.
Polysorbate 80 may also cause
infertility. A Slovakian study published in the journal Food and
Chemical Toxicology in 1993 where researchers injected female rats with
Tween 80 (in 1, 5 or 10 percent aqueous solution), on days four
through seven after birth. Tween 80 accelerated the rats’ maturation,
prolonged the estrous cycle, decreased the weight of the uterus and ovaries,
and caused damage to the lining of the uterus indicative of chronic
estrogenic stimulation. The rats’ ovaries were also damaged, with
degenerative follicles and no corpora lutea (a mass of
progesterone-secreting endocrine tissue that forms immediately after
ovulation. Severe deformities to the ovary like this can lead to
infertility.
Clinical Studies About Polysorbate
80
According an article published
at
Infertility.Suite101.com, studies were published in the journal
Annals of Allergy, Asthma and Immunology in 2005 that linked
Polysorbate 80 to nonimmunologic anaphylactoid reactions, or anaphylactoid
shock, and ultimately, to death from this reaction, including in a pregnant
woman receiving an IV drip of multi-vitamins including Polysorbate 80.
Another study published in Food Chemical Toxicology found that rats injected with
Polysorbate 80 underwent significant reproductive changes.
A
2015 study inked
polysorbate 80 to gut inflammation, negatively altered gut bacteria
jeopardizing a healthy gut biome is necessary for immune function, obesity
and metabolic syndromes.
Polysorbate 80 may allow other
vaccine ingredients to cross the blood brain barrier.
Dr. Lawrence Palevsky points out: “Polysorbate 80 is used as
an emulsifier by the pharmaceutical industry to enhance the delivery of
chemicals/drugs from the blood into the brain across the blood brain barrier
(BBB). Being that the BBB is impermeable to many things in the bloodstream,
researchers needed to find a way to deliver chemicals/drugs into the brain
from the bloodstream in order to treat hard-to-reach brain
infections/lesions/tumors, etc. Polysorbate 80 is one such chemical that
helps in this delivery.”
These studies show that after
injection polysorbate 80 breaks down into sorbitol and ethylene oxide. The
NIH toxicology network states that
sorbitol is “not to be injected,” and that
ethylene oxide is a “known carcinogen,” among other concerning toxicity
information.
This study researched the link
between the HPV vaccine and infertility. It cited the findings of the rat
study above and notes insufficient and poorly designed research on fertility
effects in clinical trials for the HPV vaccine. This study states: “The
relevance of polysorbate 80 ovarian damage to the cases presented here is
unresearched and unknown and assurances of ‘no biologically plausible’ link
between HPV4 vaccine and ovarian effects cannot be given.”
The study,
Anaphylaxis
Due to the Excipient Polysorbate 80, appeared in the Annals of
Allergy, Asthma and Immunology in December of 2005. (page 21 on the pdf
linked above) “In our conclusion, based on our results and the literature
reviewed, we believe that polysorbate 80 should be included in the test
battery for allergy to medications such as corticosteroids, since it could
be a cause of anaphylaxis of unknown etiology.”
The
NIH link for this
study notes, “Polysorbate 80 is a ubiquitously used solubilizing agent
that can cause severe nonimmunologic anaphylactoid reactions.”
Polysorbate 80 also functions
as a vaccine detergent. Detergents are used in killed virus vaccines (such
as the flu vaccine) to split or disrupt the virus particles.
Detergents cause cells to leak or
explode by weakening their cell walls. The danger is that this
process mimics our bodies’ membrane attack complex, or MAC. This link
explains in detail why this is so dangerous:
Article
Study from 2010:
"Polysorbate-80 modified neurotoxin nanoparticle with its transport and
cytotoxicity against blood-brain barrier".
Article It states: "In conclusion,
polysorbate-80 modified neurotoxin nanoparticles
can transport across the BBB,
while concentration of NT is greater than 200 ng x mL(-1), P-80-NT-NP has a
little cytotoxicity against rBMECs."
Polysorbate 80 is used as a
solubilizing agent in IV formulations of the antiarrhythmic drug amiodarone.
Rare case reports of liver toxicity have been published suggesting
polysorbate 80 may contribute to liver
toxicity with the IV formulation of amiodarone. The package labeling of
amiodarone warns that polysorbate 80 is also known to leach DEHP (dioctyl
phthalate) from PVC and dosing recommendations should be followed closely.
Acute Liver and Renal Failure: A Rare
Adverse Effect Exclusive to Intravenous form of Amiodarone. Read
study.
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