Guaifenesin (or glyceryl guaiacolate
or Guaiacum Officinale as a homeopathic remedy) is an old medication, a
synthetic version of the active compound in a tree-bark that has been used
to liquefy mucus. It has been used for conditions such as bronchial
infections, colds, sinus infections and allergies, and in clients with some
chronic lung conditions.
The 1955 edition of the Textbook of Pharmacognosy states:
"Guaiacum has a
local stimulant action which is sometimes useful in sore throat. The resin
is used in chronic gout and rheumatism, whilst the wood is an ingredient in
the compound concentrated solution of sarsaparilla, which was formerly much
used as an alternative in syphilis." Other books mention it as a treatment
for growing pains and menstrual cramps.
Guaifenesin was approved by the FDA in 1952 and was available as a
prescription pill but over the counter in various cough and cold mixtures
due to those being a lower strength.
In 2002 the FDA made a ruling that changed the guaifenesin protocol
substantially. The many brands of (generic) prescription long acting
guaifenesin were taken off the market. A more expensive over-the-counter) product, Mucinex was approved in their place. Although
Mucinex is considered a replacement for what had been on the market for so
long it really isnít quite the same. Mucinex is actually a bi-layered tablet
with a white short acting layer (100 mg) as well as a timed release blue
portion. (500 mg) This product was manufactured by Adams, but now is owned
by Reckitt Benckiser.
The Marina del Rey Pharmacy (at
developed a capsule from guaifenesin for use with the
guaifenesin protocol for fibromyalgia. It is currently available over the counter and is also sold by
mail order. This product does NOT have a short-acting part to it which is
helpful to low dose clients. This is because the short acting layer can
produce more symptoms as it reverse the fibro.
In 2013, the generic house Perrigo brought to market an
guaifenesin tablet which is 600 mg. of straight long-acting. This product
is white (no dye) but does contain compressed sugar as an additive to mask
the bitter natural taste of guaifenesin. This is marketed as a generic
product, usually in a blue and white box with red, bearing the brand name of
the pharmacy where it is sold. For example the Rite Aid product is called
Mucus Relief and the Kroger brand is Mucus-ER 12 hour. The boxes contain
the tagline ďCompare to Mucinex.Ē
It's no longer necessary to use the high doses of guaifenesin utilized in the past.
Short acting guaifenesin
when added to long acting has proven a very effective delivery system. This is due to the action of the cytochrome system which is designed
to protect the body by destroying foreign substances.
Protocol for fibromyalgia starts out on 300 mg twice a day of long-acting
guaifenesin. This should NOT be a short acting or quick release product.
Only use Mucinex or a compounded guaifenesin that is reliably longer acting. Only
20% of respond at 300 mg. twice a day. Do not use lower
doses than 600 mg. a day. If you are starting with Mucinex starting
with 900 mg. a day (1/2 in the a.m. and a full pill at night) so that you
will be getting the equivalent of at least 600 mg. of long acting in a 24 hour period.
Clients remain at 300 mg. twice a day for ONE WEEK. If
feel worse, then to increase the dose to 600 mg twice a day.
The 600 mg. twice a day is the correct dose for the next one month. Feeling
worse should be distinct like a bad flare of any or all symptoms. If you are
taking Mucinex you should go to 600 mg. morning and night OR one full pill
in the a.m. and 1 full pill in the p.m.
Left Thigh Clearing:
If the client's left thigh has not cleared to palpation after one month, or
if they notice NO CHANGE in symptoms, the dose needs to be raised
again. If a client is taking Mucinex, they should go to 3 tablets a
day. (can be taken as 1 in the a.m. --2 in the p.m. or 1 1/2 twice a day.)
If the client is taking a compounded longer acting guaifenesin from
www.fibropharmacy.com the dose can
be raised by adding a 400 mg. short acting twice a day to the 600 mg twice a
day or by adding another 600 mg. tablet.
When a higher dose is needed
\use short and long acting (2 each, twice a day). This combination is working
very well and seems to be handling between 90 - 95% of clients. If money is not an issue, 2400 mg. of Mucinex with its two layers accomplishes the same thing.
Mucinexô is the FDA approved time-released
guaifenesin 600 mg.
This can be purchased at
any pharmacy. It is a bi-layered tablet containing both long and short
acting guaifenesin. Our suggestion is that when using Mucinex begin at a
full tablet twice daily to insure enough long-acting. If reversal symptoms
are too severe then switch to the Marina del Rey 300 mg. capsules.
There are two strengths of this product available: 300 and 600 mg
should start with the 300 mg. strength (twice a day) and double that after
one week if no change is noticed. If the 300 mg. twice a day does not cause
a flare of your symptoms, you double that dose to 600 mg. twice a day and
can switch to the 600 mg. strength.
Outside the USA:
If you live outside the US you will pay less import duty if you purchase it
with a prescription. The prescription should read Guaifenesin 600 mg. dye
free. Research what your country will let you import in one shipment,
usually a 90 day supply. Check your local laws. For details contact Marina
del Rey Pharmac
Extended Release Guaifenesin 600 mg. tablets
This product is manufactured by Perrigo and is sold in pharmacies as a
generic brand. (Called things like Mucus Relief, etc.) It must say EXTENDED
RELEASE. Currently not being manufactured because of a supply issue it can
still be found by shopping around. Some pharmacies currently have it on
sale: stock up if you like this product. Also ask a manager to order some
Start this product by cutting it in half, 300 mg. twice daily. If no change
you would increase the dose by taking a full pill twice a day. After a month
the dose would be raised (if no change) to one in the morning and two at
WARNING: GUAI-AID 600 mg (and other strengths) is NOT long acting guaifenesin.
This is not suggested as a stand alone guaifenesin although it can be used as an
add-on to a longer acting product. The advertising for this product is
consistently misleading and we advise clients to avoid it for that reason.
Mucinex will work if you are taking the right dose. The problem is that when you are starting out, you must remember that one
Mucinex tablet is not 600 mg. of long acting. For a very tiny number of
people this won't matter because the amount they need to clear is less than
600 mg.a day. However, this is not the case for most people. We believe
that 99.9% of fibromyalgics need at least 600 mg of long acting a day to
clear. Since each Mucinex tablet is 100 mg of short acting and 500 mg. of
long acting, for most this isn't enough long acting. When people switch
between brands--say the Perrigo which is all long acting, they are taking
less long acting when they take Mucinex.
The second part of of this is that short acting guaifensin has a kick. Pulls a
punch. So what happens is that when people who start on Mucinex 1/2 tablet
twice a day, they feel the short acting. They hurt more so they assume they
have found the correct dose. But they do not have enough of the long acting
to continue the clearing and so they hurt but they are not clearing.
It is best for
those to start on the FibroPharmacy 300 mg
capsules, one twice a day, or the Perrigo 600mg extended release one
half-twice a day. This way, without any short acting to confuse the issue,
it is easier to find your dose.
If you start on Mucinex you can take 1/2 pill in the morning and a full pill
at night. That puts you just over the magic 600mg a day of extended release
that low dose people generally need to clear.
guaifenesin called short acting or immediate release guaifenesin is
available in 200 and 400 mg strengths. It is sold as a store
brand generic and also available
For those requiring higher doses than 1200 mg a day of long acting, you may
add short acting to save money. A long-short acting combination is very
effective: for example two long and two short twice a day seems to work for
all but extremely high dose clients.
Once you have found your dose you can add short acting as per your own
tolerance to speed up clearing.
Salicylates on the skin will
BLOCK the action of guaifenesin. Salicylate sensitivity is common. Many
people have difficulty tolerating many vegetables and fruits, aspirin, or
other medications which contain aspirin. They have allergies to plants and
pollen, or contact dermatitis when exposed to extracts or derivatives. In
1964, Dr. W.B. Shelly noted in The Journal of The American Medical
Association that a number of plants contain a "natural salicylate
radical which have the potential to induce the same kind of adverse
reactions caused by manufactured aspirin."
Salicylate sensitivity can manifest itself in many ways,
including asthma, fatigue, skin irritations, hives, rashes, increased
sensitivity, reddening of the eyes and face, changes in skin color, swelling
of the eyelids, face, and lips, photo sensitivity increased tear secretion,
headaches and hyperactivity, as well as some cognitive and perceptual
Although much attention has been given to the dietary
restrictions in these sensitive people, even small amounts of salicylate
applied topically are absorbed by the body and are known to have caused the
Gum guaiacum. Guaiacum officinale. The gum-resin of Lignum sanctum or Lignum vite, a large tree growing in W.
Indies. N. O. Zygophyllaceae. Tincture of the gum-resin.
* Rheumatic and arthritic conditions.
Mind - Mind becomes less flexible and capable.
Stiff, immobilised and slow.
- Critical from inability of mind.
- Weak memory, especially for names.
- Absentminded. Easily distracted.
- Dull, sluggish. It is an effort to think.
- Difficulty expressing ideas. Cannot say what he means.
- Answers slowly. Stares. Reflects long
- Unclear. Confusion of thoughts.
- Aversion to work, to talk. Want to be left alone. Misantrophy.
- Vacant state, as if there is nothing in the mind.
- Feel as if in a dream, unreal. Generalities - IMMOBILIZATION, CONSTRICTION, SHORTENING.
- Look like tubercular people, earthy color.
- amel. COLD APPLICATIONS (Fl-ac, Lac-c, Led, Puls, Sulph).
- agg. Exertion, motion, touch.
- agg. WARMTH.
- Burning pains.
- Desire to stretch (Rhus-t).
Food and drinks
- Desire: Apples (Ap-g, Tell, Ust).
- Aversion: Milk.
- amel. Apples.
- Sensation of swelling or actual swelling.
Eyelids appear too short.
- Frightened, staring look.
- Old looking.
- Left sided neuralgia, amel. pressure, agg. 6 p.m. to 4 a.m. . Daily.
- Rheumatic sore throat with weak throat muscles.
- Constriction and burning pain, amel. apples.
- Ovaritis in rheumatic women. Dysmenorrhea.
- Pleuritic stitches.
- painful stiffness, agg. motion.
- Sciatica, lumbago agg. warmth.
- ARTHRITIS, CARPAL TUNNEL SYNDROME OF LEFT WRIST (right: Viol-o).
- ARTHRITIC, RHEUMATIC, GOUTY PAIN often with sensation of heat in affected
amel. COLD APPLICATIONS (Lac-c, Led, Puls, Sulph).
agg. Warmth, exertion, motion, pressure.
Joints mostly affected: wrists, knees, ankles.
- Abscesses in swollen joints.
- Tendons shortened, swollen, stiff (Caust, Plb, Ruta). Contracted, especially
- Immovable stiffness.
- Growing pains (Calc-p).
- Nightmares when lying on the back. Wakes screaming.
chemical compound, Vitamin D participates in many metabolic pathways. In each
it's role is different. So if you are trying to dump phosphates, you may not
want too much of it around. The below pathway for phosphates assumes that body
is regulating Vitamin D. If the body is getting extra vitamin D in absence low
phosphate diet. Guaifenesin plays a role somewhere along this pathway - and
Vitamin D will be in direct opposition to it.
Miracles Find You!ô"
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