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Neurotransmitter Sarcodes
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Neurotransmitter Sarcodes Used In Homeopathy
Homeopathic sarcodes and remedies have a direct impact on neurotransmitter function.  Contact us to learn more!

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  • Acetylcholine
    Acetylcholine was the first neurotransmitter to be discovered.  It has many functions.  It is responsible for much of the stimulation of muscles, including the muscles of the gastro-intestinal system.  It is also found in sensory neurons and in the autonomic nervous system, and has a part in scheduling REM or dream sleep.

  • Endorphin
    Endorphin is endogenous morphine since it is structurally very similar to the opioids (opium, morphine, heroin, etc.) and has similar inhibitory functions. It is involved in pain reduction and pleasure, and the opioid drugs work by attaching to endorphin's receptor sites.  It allows bears and other animals to hibernate. 

  • Dopamine
    Dopamine  is an inhibitory neurotransmitter, when it finds its way to its receptor sites; it blocks the tendency of that neuron to fire.  Dopamine is synthesized in cell groups in the midbrain's substantia nigrae and ventral tegmental areas (VTA). It is strongly associated with reward mechanisms in the brain. There are eight neural pathways, called dopaminergic pathways, in the brain that function via dopamine transmission.

  • Endorphin
    Endorphin is endogenous morphine since it is structurally very similar to the opioids (opium, morphine, heroin, etc.) and has similar inhibitory functions. It is involved in pain reduction and pleasure, and the opioid drugs work by attaching to endorphin's receptor sites.  It allows bears and other animals to hibernate. 

  • GABA
    GABA (gamma aminobutyric acid) is usually an inhibitory neurotransmitter.  GABA acts like a brake to the excitatory neurotransmitters that lead to anxiety.  People with too little GABA tend to suffer from anxiety disorders. If GABA is deficient in certain parts of the brain, epilepsy fallouts.

  • Epinephrine
    Epinephrine or adrenaline is a catecholamine. Many kinds of reactions convert tyrosine to dopamine, to norepinephrine, and eventually to epinephrine.

    • Epinephrine drives the autonomic nervous system's fight-or-flight response. It is synthesized in the adrenal glands and released into the bloodstream when dangerous circumstances occur, in an emergency requiring immediate action, and in stressful situations or environments. When in the bloodstream, epinephrine rapidly prepares the body for action. It boosts the supply of oxygen and glucose to the brain and muscles while suppressing other non-emergency bodily processes, especially digestion.

    • Epinephrine increases heart rate and stroke volume, dilates the pupils, and constricts arterioles in the skin and gastrointestinal tract while dilating arterioles in skeletal muscles. It increases catabolism of glycogen to glucose in the liver, thereby elevating the blood sugar level. At the same time, epinephrine begins the breakdown of lipids in fat cells. Epinephrine has a suppressive effect on the immune system. Stress tends to deplete store of adrenalin, while exercise tends to increase it.

    • Axon terminals of the sympathetic nervous system release norepinephrine into the adrenal glands. Epinephrine is derived from norepinephrine via methylation of norepinephrine's primary distal amine by phenylethanolamine N-methyltransferase (PNMT) in the cytosol of adrenergic neurons and chromaffin cells of the adrenal medulla. PNMT is only found in the cytosol of cells of adrenal medullary cells. PNMT uses S-adenosylmethionine (SAMe) as a cofactor to donate the methyl group to norepinephrine, creating epinephrine.

    • The hypothalamus prompts the anterior lobe of the pituitary gland to release adrenocorticotropic hormone (ACTH) into the bloodstream. ACTH stimulates the adrenal cortex to release cortisol, which increases the expression of PNMT in chromaffin cells, enhancing epinephrine synthesis and release into the bloodstream. ACTH also enhances the activity of enzymes involved in catecholamine synthesis, thereby stimulating the synthesis of epinephrine precursors. These specific enzymes are tyrosine hydroxylase in the synthesis of dopamine and the enzyme dopamine--hydroxylase in the synthesis of norepinephrine.
       

  • Glutamate
    Glutamate is an excitatory relative of GABA.  It is the most common neurotransmitter in the central nervous system and is especially important in regards to memory.  Interestedly, glutamate is actually toxic to neurons, and an excess may kill them.  Sometimes brain damage or a stroke lead to an excess and end with many more brain cells dying than from the original trauma.  ALS or Lou Gehrig's disease, results from excessive glutamate production. 

  • Norepinephrine or noradrenaline

    • Norepinephrine or noradrenaline is strongly associated with bringing nervous system into "high alert."  Neurons in the loci coerulei, a pair of structures located within the pons of the brain stem, synthesize norepinephrine. The axons of neurons in the loci coerulei project to both sides of the brain where they release norepinephrine. A single neuron in the locus coeruleus can innervate tissue in wide-ranging areas. The branching axons of norepinephrine-producing neurons in the loci coerulei innervate the brain stem, spinal cord, and cerebellum, as well as the hypothalami, thalamic relay nuclei, amygdalae, and neocortex.

    • Norepinephrine is predominant in the sympathetic nervous system, and it increases our heart rate as well as the blood pressure. It relays messages in the sympathetic nervous system, as part of the autonomic nervous system's fight-or-flight response. Secondly, norepinephrine prepares the brain to encounter and respond to stimuli from the environment, thereby facilitating vigilance. So in both roles, norepinephrine mediates arousal. Adrenal glands release it into the blood stream, along with its close relative epinephrine or adrenaline.  It is also important for forming memories.

  • Serotonin

    • Serotonin is an inhibitory neurotransmitter that has been found to be closely involved in emotion and mood.  Too little serotonin has been shown to lead to depression, problems with anger control, obsessive-compulsive disorder, and suicide.  Too little serotonin also leads to an increased appetite for carbohydrates and trouble sleeping, which are also associated with depression and other emotional disorders.  It is also responsible for migraines, irritable bowel syndrome, and fibromyalgia.

    • Serotonin is a derivative of tryptophan, which is found in milk. Serotonin also plays a role in perception. Sense of well-being and capacity to organize lives and to relate to others depend profoundly on the functional integrity of the serotonergic system. Roughly one millionth of the total population of neurons in the human central nervous system are serotonergic neurons. Fourteen types of serotonin receptors have been discovered so far in the brains of mammals, located in different places and acting in different ways. Most serotonin in the human body is found in the enterochromaffin cells in the gastrointestinal tract, where it is used to regulate intestinal movements. In the brain, the neurons of the raphe nuclei are the principal source of serotonin release.



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