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Polysorbate 80 In Vaccines and Medications

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Polysorbate 80 (Tween 80) In Vaccines and Medications

Homeopathy can provide a effective, natural detoxification from exposures to polysorbate 80 (Tween 80).
Contact us to learn more!

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What Is Polysorbate 80?

Polysorbate 80 is surfactant  that is Tween 80, Polyoxyethylene (20) sorbitan monooleate, and POE (20) sorbitan monooleate. It is a brain toxic excipient added to vaccines and medications that crosses the blood brain barrier. It allows nano particles to enter the brain, causing inflammation.  Polysorbate 80 (brand names include Alkest, Canarcel and Tween, which is a registered trademark of ICI Americas, Inc.) is a nonionic surfactant, a compound which lowers the surface tension between two liquids or between a liquid and a solid. Surfactants may act as detergents, wetting agents, emulsifiers, foaming agents, and dispersants.

Current Uses of Polysorbate 80

  • Polysorbates are widely used in cosmetics, food products, and oral, parenteral, and topical pharmaceutical formulations. It is generally regarded as nontoxic and nonirritant materials. However, been occasional reports of hypersensitivity to polysorbates following their topical and intramuscular use. Polysorbates have also been associated with serious adverse effects, including some deaths, in low birth weight infants intravenously administered a vitamin E preparation containing a mixture of polysorbates 20 and 80.

  • Polysorbate 80 is used as an emulsifier by the pharmaceutical industry to enhance the delivery of chemicals and drugs from the blood into the brain across the blood brain barrier (BBB). Being that the BBB is impermeable to many things in the bloodstream, researchers needed to find a way to deliver chemicals/drugs into the brain from the bloodstream in order to treat hard-to-reach brain infections/lesions/tumors, etc.

  • Polysorbate 80 is one such chemical that helps in this delivery. Read more here.

Why Is Polysorbate 80 Dangerous?

  • They primary danger of polysorbate 80 (Tween 80) is that it helps deliver compounds and this includes mercury and aluminum, across the blood-brain barrier (BBB). The blood-brain barrier is weak and easily crossed during the first two or three years of life and often during the senior years. In other age groups the blood-brain barrier which normally restricts passage of substances from the bloodstream. Polysorbate 80 in vaccines may allow other vaccine ingredients to enter the brain. 

  • Polysorbate 80 is more dangerous when combined with other risky vaccine ingredients. It is present in DTaP, Gardasil (HPV), Hep A, Influenza vaccines, Meningitis, Polio, Pneumococcal, Rotavirus, Tdap and Vitamin K shots,  as well as other  vaccines and medications.

  • Polysorbate 80 is used as a vaccine emulsifier. Many studies confirm that polysorbate 80 can increase cell permeability, damage and bursting.

  • Polysorbate 80 may increase increase the risk of diabetes as well as cell death, mitochondrial failure and DNA fragmentation. After injection in a vaccine, it can quickly break down into sorbitol and ethylene oxide. Sorbitol is connected with these aforementioned risks.

  • Polysorbate 80 from vaccines has also been shown to abruptly change heart function. A drug used to treat anemia related to chronic kidney disease and chemotherapy warns: Clinical studies have shown polysorbate 80 to increase the risk of serious side effects such as blood clots, stroke, heart attack, heart failure and death in some cases.

  • Polysorbate 80 has also been shown to shorten overall survival and/or increase the risk of tumor growth or recurrence in those with certain types of cancer.

  • Polysorbate 80 can cause hypersensitivity reactions and anaphylaxis. It is very risky in infants. The risk is increases when polymyxin B, another vaccine ingredient is also present.

  • Polysorbate 80 is more dangerous for infants through the Vitamin K shot and other childhood vaccines. It is made from  sorbitol,  a plant-based sugar alcohol and oleic acid, a fatty acid. It’s used in ice cream to make it smoother and it serves a similar purpose in the vitamin K shot. It is an emulsifier, helping fat-soluble vitamin K stay in solution. The ingredients in a Vitamin K shot with NO preservatives include 10 mg of polysorbate 80.

  • Polysorbate 80 may also cause infertility. A Slovakian study published in the journal Food and Chemical Toxicology in 1993 where researchers injected female rats with Tween 80 (in 1, 5 or 10 percent aqueous solution), on days four through seven after birth. Tween 80 accelerated the rats’ maturation, prolonged the estrous cycle, decreased the weight of the uterus and ovaries, and caused damage to the lining of the uterus indicative of chronic estrogenic stimulation. The rats’ ovaries were also damaged, with degenerative follicles and no corpora lutea (a mass of progesterone-secreting endocrine tissue that forms immediately after ovulation. Severe deformities to the ovary like this can lead to infertility.

Clinical Studies About Polysorbate 80

  • According an article published at Infertility.Suite101.com, studies were published in the journal Annals of Allergy, Asthma and Immunology in 2005 that linked Polysorbate 80 to nonimmunologic anaphylactoid reactions, or anaphylactoid shock, and ultimately, to death from this reaction, including in a pregnant woman receiving an IV drip of multi-vitamins including Polysorbate 80.

  • Another study published in Food Chemical Toxicology found that rats injected with Polysorbate 80 underwent significant reproductive changes.

  • A 2015 study inked polysorbate 80 to gut inflammation, negatively altered gut bacteria jeopardizing a healthy gut biome is necessary for immune function, obesity and metabolic syndromes.

  • Polysorbate 80 may allow other vaccine ingredients to cross the blood brain barrier. Dr. Lawrence Palevsky points out: “Polysorbate 80 is used as an emulsifier by the pharmaceutical industry to enhance the delivery of chemicals/drugs from the blood into the brain across the blood brain barrier (BBB). Being that the BBB is impermeable to many things in the bloodstream, researchers needed to find a way to deliver chemicals/drugs into the brain from the bloodstream in order to treat hard-to-reach brain infections/lesions/tumors, etc. Polysorbate 80 is one such chemical that helps in this delivery.”

  • These studies show that after injection polysorbate 80 breaks down into sorbitol and ethylene oxide. The NIH toxicology network states that sorbitol is “not to be injected,” and that ethylene oxide is a “known carcinogen,” among other concerning toxicity information.

  • This study researched the link between the HPV vaccine and infertility. It cited the findings of the rat study above and notes insufficient and poorly designed research on fertility effects in clinical trials for the HPV vaccine. This study states: “The relevance of polysorbate 80 ovarian damage to the cases presented here is unresearched and unknown and assurances of ‘no biologically plausible’ link between HPV4 vaccine and ovarian effects cannot be given.”

  • The study, Anaphylaxis Due to the Excipient Polysorbate 80, appeared in the Annals of Allergy, Asthma and Immunology in December of 2005. (page 21 on the pdf linked above) “In our conclusion, based on our results and the literature reviewed, we believe that polysorbate 80 should be included in the test battery for allergy to medications such as corticosteroids, since it could be a cause of anaphylaxis of unknown etiology.”

  • The NIH link for this study notes, “Polysorbate 80 is a ubiquitously used solubilizing agent that can cause severe nonimmunologic anaphylactoid reactions.”

  • Polysorbate 80 also functions as a vaccine detergent. Detergents are used in killed virus vaccines (such as the flu vaccine) to split or disrupt the virus particles. Detergents cause cells to leak or explode by weakening their cell walls. The danger is that this process mimics our bodies’ membrane attack complex, or MAC. This link explains in detail why this is so dangerous: Article

  • Study from 2010: "Polysorbate-80 modified neurotoxin nanoparticle with its transport and cytotoxicity against blood-brain barrier". Article It states: "In conclusion, polysorbate-80 modified neurotoxin nanoparticles can transport across the BBB, while concentration of NT is greater than 200 ng x mL(-1), P-80-NT-NP has a little cytotoxicity against rBMECs."

Polysorbate 80 Use In Vaccines in the USA

Polysorbate 80 is used as an emulsifier/stabilizer in vaccines but you won’t find any safety information from CDC documents.
It’s not even listed on the CDC Ingredients of Vaccines Fact Sheet Download Vaccine Excipients Chart from CDC

  • DTaP (Infanrix)
  • DTaP—IPV (Kinrix)
  • DTaP – IPV (Quadracel)
  • DTap-HepB-IPV (Pediarix)
  • DTaP-IPV-Hib (Pentacel)
  • Gardasil (Merck)
  • Gardasil 9 (Merck)
  • Hep A (Havrix)
  • Hep A/Hep B (Twinrix)
  • IPV Inactivated Polio Vaccine  (Sanofi Pasteur)
  • Infanrix™-hexa (GlaxoSmithKline)
  • Influenza (Fluad)
  • Influenza (Fluarix) Trivalent & Quadrivalent
  • Influenza (Flublok) Trivalent & Quadrivalent
  • Influenza (Flucelvax) Trivalent & Quadrivalent
  • Influenza (Flulaval) Trivalent & Quadrivalent
  • Meningococcal (MenB – Trumenba)
  • Pneumococcal (PCV13 – Prevnar 13)
  • Tdap (Boosterix)
  • Vitamin K

Polysorbate 80 in Vaccines in the Canada

  • Adacel (Sanofi Pasteur)
  • Adacel - Polio (Sanofi Pasteur)
  • Agriflu (Novartis)
  • BCG vaccine (Freeze-Dried) (Sanofi Pasteur)
  • Fluad (Novartis)
  • Gardasil (Merck Frosst)
  • Inactivated Polio Vaccine – IPV (Sanofi Pasteur)
  • Infanrix-Hexa (GlaxoSmithKline)
  • Influva (Abbott)
  • Pediacel (Sanofi Pasteur)
  • Pentacel (Sanofi Pasteur)
  • Quadracel (Sanofi Pasteur)
  • Td Polio Adsorbed (Sanofi Pasteur)

Polysorbate 80 in Drugs and Antibiotics

Polysorbate 80 is used as a solubilizing agent in IV formulations of the antiarrhythmic drug amiodarone. Rare case reports of liver toxicity have been published suggesting polysorbate 80 may contribute to liver toxicity with the IV formulation of amiodarone. The package labeling of amiodarone warns that polysorbate 80 is also known to leach DEHP (dioctyl phthalate) from PVC and dosing recommendations should be followed closely.

Acute Liver and Renal Failure: A Rare Adverse Effect Exclusive to Intravenous form of Amiodarone. Read study.

Antibiotics With Polysorbate 80 (Tween-80)

  • Amoxicillin
  • Azithromycin Teva
  • Doxycycline
  • Tetracycline
  • Vancomycin
  • Zithromax Z-Pak oral

Drugs With Polysorbate 80 (Tween-80)
See drug list here https://www.drugbank.ca/drugs/DB11063

  • Celexa
  • Lamotrigine
  • Amitriptyline Hydrochloride 25 mg
  • Amiodarone
  • Cyclobenzaprine Hydrochloride 10 mg
  • Escitalopram Oxalate 10 mg
  • Gabapentin 600 mg
  • Gabapentin 800 mg
  • Hydroxychloroquine Sulfate 200 mg
  • Hydroxyzine Hydrochloride 25 mg
  • LUVOX (fluvoxamine maleate)
  • Nexium
  • OxyContin 20 mg
  • OxyContin 40 mg
  • OxyContin 30 mg
  • Paxil (paroxetine hydrochloride)
  • Paxil Controlled-Release tablets
  • Prozac
  • Sertraline Hydrochloride 50 mg
  • Sertraline Hydrochloride 100 mg
  • Tramadol Hydrochloride 50 mg
  • Wellbutrin
  • Zoloft (Sertaline)

What Is Polysorbate 80?
(6:01 minutes)

 




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